Impact of NRS 2002 Score Combined with Enteral Immune Microenvironmental Nutrition on Intestinal Microecology in Patients with Severe Pneumonia
[Objective]To study the effects of Nutrition Risk Screening 2002(NRS2002)score support combined with enteral immune microecological nutrition the on the gut microbiota and inflammatory factors in patients with severe pneumonia(SP).[Method]Totally 98 patients with SP admitted to the Department of Critical Care Medicine of our hospital from April 2022 to December 2023 were randomly divided into two groups,with 49 cases in each group,using a random number table method.The control group received routine nutritional support,while the observation group received support based on NRS 2002 score combined with intestinal immune microecological nutri-tion.Compare the NRS 2002 score,gut microbiota content,inflammatory factors,and adverse risk events before and after treatment between two groups.[Result]After treatment,the NRS2002 scores,HMGB1,MCP-1,IL-6 levels,and logarithmic values of Enterococ-cus colonies in both groups decreased compared to before treatment,while the logarithmic values of Lactobacillus,Bifidobacterium,and Escherichia coli colonies increased compared to before treatment.In addition,the NRS 2002 nutritional risk score,expression of inflamma-tory factors mentioned above,and logarithmic values of Enterococcus colonies in the observation group were lower than those in the control group,while the logarithmic values of Lactobacillus,Bifidobacterium,and Escherichia coli colonies were higher than those in the control group(P＜0.05).The incidence of adverse events related to nutritional support in the observation group was lower than that in the control group(P＜0.05).[Conclusion]The application of enteral immune microbiota nutrition based on the NRS 2002 score supportin the nutritional management of SP patients has significant effect,which can effectively improve inflammatory factors and nutritional status,reduce the risk of adverse events and intestinal microbiota imbalance.
severe pneumoniaNRS 2002 scoreintestinal microbiotainflammatory factor
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