Effect of Vitamin D Combined with Enteral Nutrition Intervention on Nutritional Status and Prognosis of Patients with Liver Cirrhosis with Oesophagogastric Fundal Vein Haemorrhage
[Objective]To exploring the effects of vitamin D combined with enteral nutritional support on liver function,nutritional status,and prognosis of patients with liver cirrhosis with oesophagogastric fundus vein haemorrhage.[Method]Totally 100 patients with liver cirrhosis with oesophagogastric fundal vein bleeding who were hospitalised in our hospital from January 2023 to December 2023 were collected and randomly divided into the vitamin D combined enteral nutrition intervention group(observation group)and the control group using a random number table,and the control group was given conventional treatment and intervention,while the observation group patients were given vitamin D and enteral nutrition intervention on top of it,and the intervention of the patients of the two groups was compared.Changes in liver function indexes and nutritional indexes before and after the intervention,as well as the differences in gastrointestinal reactions,incidence of rebleeding,and hospitalisation time.[Result]After the intervention,the serum liver function indexes(ALT,AST and GGT)of the two groups of patients decreased compared with the pre-intervention period,and the serum nutritional indexes(PA,TP and ALB)increased compared with the pre-intervention period,and the difference was statistically significant(P<0.05),and the improvement of the liver function and nutritional status of the patients in the observation group was better than that of the control group after the intervention,and the difference was statistically significant(P<0.05).The incidence of adverse gastrointestinal reactions in the observation group was 8%,which was significantly lower than that in the control group(incidence of 32%,χ2=9.000,P=0.003).The incidence of rebleeding was significantly lower in the observation group than in the control group(4%vs 16%,P=0.046).The mean length of stay in the observation group was significantly lower than that in the control group[(11.00±2.222)days vs.(15.90±1.418)days,P<0.001)].[Conclusion]Vitamin D combined with enteral nutritional support improves liver function in patients with cir-rhosis with oesophagogastric fundal variceal bleeding,improves nutritional status,and reduces the incidence of adverse gastrointestinal reactions,the incidence of rebleeding,and the length of hospital stay,which is worthy of being promoted and applied clinically.
vitamin Denteral nutritionoesophagogastric fundal vein haemorrhage in cirrhosisliver functionnutritional statusprognosis
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