Effects of folic Acid Supplementation on Cognitive Function and Prognosis in Elderly Patients with Cerebral Infarction
[Objective]To investigate the effect of folic acid supplementation on cognitive function and prognosis in elderly patients with cerebral infarction.[Method]Totally 60 elderly patients with cerebral infarction were selected for treatment in Suzhou First People's Hospital from January 2023 to December 2023,including 30 cases in the observation group and 30 cases in the control group.The control group was treated with antiplatelet and other conventional treatments for 4 weeks,and the observation group was treated with folic acid tablets,5 mg each time once a day for 4 weeks.Serum homocysteine(Hcy)levels were measured before and after treatment,the cognitive function of the two groups was assessed by Mini-Mental State Examination(MMSE),the neurological impairment of the patients was evalu-ated by the NIH Stroke Scale(NIHSS),and the prognosis of the patients was evaluated by the modified Rankin scale(mRS).[Result]After treatment,the serum Hcy level and MMSE score of the observation group were(13.17±2.20)µmol/L and(25.76±1.21)points,and the NIHSS score of the observation group was(3.13±1.12)and the mRS score was(1.37±0.31),which showed a statistical differ-ence between the observation group and the control group(P<0.05).[Conclusion]Folic acid supplementation can effectively lower the Hcy in old patients with cerebral infarction,and improve the cognitive function and neurological function deficits and prognosis.
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