[Objective]With volcanic Pueraria thomsonii Benth as raw material,Dendrobium officinale,maltodextrin,xylitol and sodium alginate as excipients,Pueraria thomsonii mixing powders was prepared.[Method]Through single factor and L9(34)orthogonal experiment,the optimal formula of Pueraria thomsonii mixing powders was determined by comprehensive scoring method.The total antioxidant capacity of the powders was determined by DPPH·free radical scavenging ability and ABTS+·free radical scavenging ability.The hypoglycemic effect of powders in vitro was determined by the inhibitory activity test of α-glucosidase.[Result]The optimal formula of the powder was the ratio of raw materials(Pueraria thomsonii:Dendrobium officinale)1:0.2,maltodextrin 10％,xylitol 0.3％,sodium alginate 0.3％,and the comprehensive score was 84.65 points.The IC50 values of scavenging ABTS+·free radicals by Puerariae thomsonii mixing powders and ascorbic acid were(3.909±0.975)and(0.200 9±0.084 9)mg/mL,respectively.The IC50 values of DPPH·free radi-cal scavenging of Pueraria thomsonii mixing powders and ascorbic acid were(3.860±1.094)and(0.126 9±0.075 5)mg/mL,respectively.The total antioxidant capacity of Puerariae thomsonii mixing powders and ascorbic acid at a concentration of 1.5 mg/mL was 0.181 1 and 0.499,respectively.The IC50 values of α-glucosidase inhibitory activity of Pueraria thomsonii mixing powders and acarbose were(5.845±3.353)and(0.371±0.047 7)mg/mL,respectively.[Conclusion]A new powder blending product of Pueraria thomsonii was developed to improve its economic value.
万方数据
维普
