[Objective]Comprehensive understanding of the relationship between vitamin B1 and chronic diseases,to provide scientific basis for nutritional supplementation.[Method]This paper reviewed research progress of the relationship between vitamin B1 and chronic diseases.[Result]Vitamin B1 supplementation may have potential health effect on the prevention and treatment of type 2 diabetes,Alzheimer's disease and other chronic diseases.[Conclusion]Supplementation with the appropriate dose of vitamin B1 and its derivatives could be beneficial in reducing the risk of type 2 diabetes and improving cognition in patients with Alzheimer's disease.
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