Distribution of Lipid Soluble Vitamin Levels in Elderly Patients with Coronary Heart Disease and Their Correlation with The Severity of Disease
[Objective]To explore the distribution of lipid soluble vitamin levels in elderly patients with coronary heart disease and their correlation with the severity of the condition.[Method]Totally 82 elderly patients with coronary heart disease who were treated in our hospital from January 2022 to February 2024 were selected as the observation group.At the same time,30 patients with coronary heart disease excluded from CAG examination due to chest discomfort during the same period were selected as the control group.The serum levels of vitamin D,E,A,and K1 were observed in the two groups,and the differences between patients with different degrees and types of lesions were compared.[Result]The vitamin D in the observation group was(22.41±6.40)nmol/L,which was significantly lower than the control group(P<0.05),while vitamin E,vitamin K1,and vitamin A were(14.25±2.22),(1.44±0.35),and(72.25±13.35)ng/mL,respectively,which was significantly higher than the control group(P<0.05).The vitamin D of the observation group with severe le-sions was(15.84±6.11)nmol/L,which was significantly lower than that of mild and moderate lesions(P<0.05),while vitamin E,vitamin K1,and vitamin A were(17.47±2.00)μg/mL,(1.80±0.24)ng/mL,and(79.80±11.87)ng/mL,respectively,which was significantly higher than those of mild and moderate lesions(P<0.05).The vitamin D levels in the observation group of patients with acute myocardial infarction were(20.07±5.06)nmol/L,significantly lower than those in the un-stable angina patients(P<0.05),while vitamin E,vitamin K1,and vitamin A levels were(17.47±2.00)μg/mL,(1.80±0.24)ng/mL,and(79.80±11.87)ng/mL,respectively,which was significantly higher than those in the un-stable angina patients(P<0.05).Vitamin D was negatively correlated with severity(r=-0.362,P<0.05),while vitamin E,vitamin K1,and vitamin A were positively correlated with severity(r=0.800,0.786,and 0.236,μg/L<0.05).[Conclusion]The levels of vitamin D in elderly patients with coronary heart disease decrease,while the levels of vitamin E,K1,and A increase.Among them,vitamin D is negatively correlated with the severity of the disease,while vitamin E,K1,and A are positively correlated with the severity of the disease.
elderly peoplecoronary heart diseasefat soluble vitamindegree of illnesscorrelation