Research Progress on Extraction,Separation and Biological Activity of Natural Biflavonoids
[Objective]Natural biflavonoids are low-molecular-weight polyphenols in nature and exhibit high biological activity.The method of extracting active ingredients from herbal medicines and using them has been the key research direction in research.Therefore,summarizing the extraction,separation and purification methods of bisflavonoids and their biological activities in recent years is of great significance.[Method]The distribution,extraction,separation and purification methods of bisflavonoids and the biological activities of bisflavonoids were searched using CNKI and ScienceDirect databases,respectively.[Result]The extraction,separation and purification methods of bisflavonoids at home and abroad,and the effects of bisflavonoids such as antioxidant,anti-inflammatory,inhibiting cancer cells,antiviral,antibacterial,etc.were summarized,which provided theoretical basis for the further development and utilization of bisflavonoids.[Conclusion]There is still a lot of place for development in the function,development and utilization of biflavonoids,and there is a big gap in the research on dosage forms,which needs further research and supplementation.
biflavonoidsextraction methodpurification and separation methodbiological activity