首页|浦东新区16~45岁常住女性HPV疫苗相关KAP及其影响因素分析

浦东新区16~45岁常住女性HPV疫苗相关KAP及其影响因素分析

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目的 分析上海市浦东新区16~45岁常住女性对人乳头瘤病毒(human papilloma virus,HPV)疫苗的相关知识、态度、行为(knowledge-attitude-practice,KAP)及其影响因素.方法 在浦东新区36个街镇中随机选取6个作为调查现场,随机抽样选取16~45周岁常住女性,排除阅读或理解障碍者、有精神障碍者,通过自填式问卷共收集到1 022份有效问卷,了解浦东新区常住女性对HPV疫苗的KAP现状,通过单因素分析和结构方程模型分析HPV疫苗的KAP之间的联系及其影响因素.结果 浦东新区16~45岁常住女性对HPV疫苗的总体知晓率较高,单因素分析显示,婚姻状况、文化程度、就业状况及家庭年收入与HPV疫苗的知晓水平有关(x2分别为12.832、17.636、16.770和20.030,P均<0.05);年龄、婚姻状况、就业情况、子女情况与HPV疫苗的接种水平有关(x2分别为12.382、25.777、8.830和20.138,P均<0.05);HPV疫苗健康教育、HPV及HPV疫苗知识得分影响HPV疫苗的接种情况(x2分别为97.561和68.969,P<0.001);研究对象对于宫颈癌知识的掌握受HPV感染相关知识的正向影响(γ11=0.756,P<0.001).宫颈癌知识的掌握程度不仅会正向影响研究对象对HPV疫苗功效的态度(β21=0.557,P<0.001),也会直接影响研究对象HPV疫苗的接种行为,表现为促进作用(β31=0.274,P=0.004).研究对象对HPV疫苗功效表示赞同的态度与HPV疫苗实际接种行为呈正向作用(β32=0.175,P=0.016).结论 浦东新区16~45岁常住女性接种HPV疫苗的意愿积极,但实际接种率较低,建议增强HPV疫苗宣传的同时增强宫颈癌及HPV感染相关知识的教育,并考虑将适龄男性纳入疫苗接种范围的必要性.
Analysis of HPV vaccine-related KAP and its influencing factors among resident women aged 16-45 years in Pudong New Area
Objective To analyze the related knowledge-attitude-practice(KAP)and the influencing factors of human papilloma virus(HPV)vaccine among 16-45 year old resident women in Pudong New Area.Methods Six of the 36 streets(towns)in Pudong New Area were randomly selected as the survey site,the resident women aged 16-45 years were randomly selected excluding those with reading or comprehension disabilities and those with mental disorders,and a total of 1 022 valid questionnaires were collected through self-filling questionnaires to understand the KAP status of the HPV vaccine among the resident women in Pudong New Area.The relationship among KAP of HPV vaccine and its influencing factors were analyzed by univariate analysis and structural equation model.Results The overall awareness rate of HPV vaccine among 16-45 year old resident women in Pudong area was higher.Univariate analysis showed that marital status,educational level,employment status and household annual income were related to the awareness level of HPV vaccine(x2=12.832,17.636,16.770 and 20.030,respectively,each P<0.05);Age,marital status,employment status and children's status were correlated with HPV vaccination level(x2=12.382,25.777,8.830 and 20.138,respectively,each P<0.05);HPV vaccine health education,HPV and HPV vaccine knowledge scores affected HPV vaccination status(x2=97.561 and 68.969,respectively,P<0.001);Subjects'knowledge of cervical cancer was positively affected by know-ledge of HPV infection(γ11=0.756,P<0.001).Knowledge of cervical cancer not only positively affected subjects'atti-tudes towards the efficacy of HPV vaccine(β21=0.557,P<0.001),also had a direct effect on the HPV vaccination beha-vior of the subjects,showing a promoting effect(β31=0.274,P=0.004).Subjects'approval of the efficacy of HPV vaccine had a positive effect on their actual vaccination behavior(β32=0.175,P=0.016).Conclusion The willingness of the 16-45 year old resident women in Pudong New Area to inoculate HPV vaccine was positive,but the actual vaccination rate was low.It is suggested to strengthen the HPV vaccine publicity while strengthening the education of cervical cancer and HPV infection,and consider the necessity of including the suitable age males in the scope of human vaccination.

Pudong New AreaHuman papilloma virus(HPV)vaccineKnowledge-attitude-practice(KAP)

王卫平、刘文敏、杨丹丹、揭俊钦、杜莉、周萍、文京海

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上海市浦东新区疾病预防控制中心免疫科复旦大学浦东预防医学研究院,上海 200136

复旦大学公共卫生学院 国家卫生健康委卫生技术评估重点实验室,上海 200032

上海市妇幼保健中心科教科,上海 200062

浦东新区 人乳头瘤病毒疫苗 知识、态度、行为

浦东新区卫生健康委员会卫生计生科研项目浦东新区科技发展基金上海市公共卫生体系建设三年行动计划项目上海市公共卫生体系建设三年行动计划项目上海市卫生健康委员会课题

PW2019A-2PKJ2023-Y34GWV-10.2-XD08GWV-9.4201940076

2024

中国生物制品学杂志
中华预防医学会,长春生物制品研究所有限责任公司

中国生物制品学杂志

CSTPCD
影响因子:0.417
ISSN:1004-5503
年,卷(期):2024.37(2)
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