首页|2020年吉林省乙型病毒性肝炎血清流行病学调查分析

2020年吉林省乙型病毒性肝炎血清流行病学调查分析

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目的 评价2020年吉林省乙型病毒性肝炎(简称乙肝)血清流行特征.方法 采用分层多阶段整群随机抽样方法,2020年抽取吉林省1~69岁人群1 667人,开展现场乙肝流行病学调查,并采集血清标本,利用ELISA法检测乙型肝炎病毒(hepatitis B virus,HBV)表面抗原(HBsAg)、HBV表面抗体(HBsAb)、HBV核心抗体(HBcAb),HBVE抗原(HBeAg)和HBVE抗体(HBeAb),应用全国流行病学动态数据采集平台,SPSS 18.0软件进行数据分析.结果 2020年调查的各年龄组乙肝疫苗接种率差异有统计学意义(x2=810.48,P<0.05).2020年吉林省1~69岁人群HBsAg携带率为0.96%,HBsAb阳性率为59.99%,HBV感染率为15.66%,HBeAb阳性率为7.02%,HBeAg阳性率为0.18%.结论 2020年吉林省HBV感染标志物各项指标良好,应继续保持人群的高接种率,同时应加强成人乙肝疫苗接种,降低成人的感染风险.
Investigation and analysis on hepatitis B serum epidemiology in Jilin Province in 2020
Objective To assess the epidemic characteristics of serum of viral hepatitis type B(hepatitis B for short)infec-tion in Jilin Province in 2020.Methods In 2020,1 667 people ranging in age from 1 to 69 years in Jilin Province were selected by using multi-stage random sampling method for field epidemiological investigation of hepatitis B.The serum samples were collected and detected for the hepatitis B virus(HBV)surface antigen(HBsAg),HBV surface antibody(HBsAb),HBV core antibody(HBcAb),HBV E antigen(HBeAg)and HBV E antibody(HBeAb)by ELISA,and the data were analyzed by the national epidemiological dynamic data collection platform,SPSS 18.0 software.Results There were significant differences in hepatitis B vaccination rates across age groups surveyed in 2020(x2=810.48,P<0.05).In 2020,the HBsAg carrying rate,HBsAb positive rate,HBV infection rate,HBeAb positive rate and HBeAg positive rate of people at the age of 1-69 years in Jilin Province were 0.96%,59.99%,15.66%,7.02%and 0.18%,respectively.Conclusion In 2020,the indicators of HBV infection in Jilin Province were good,and the high vaccination rate of people should continue to be maintained,and the vaccination of hepatitis B vaccine for adults should be strengthened to reduce the risk of infection in these susceptible groups.

Hepatitis BHepatitis B virus(HBV)Serum epidemiology investigation

付思美、曹凤瑞、程涛、李春梅、李永强、王爽、武懿

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吉林省疾病预防控制中心免疫规划所,吉林长春 130062

乙型病毒性肝炎 乙型肝炎病毒 血清学调查

中华预防医学会疫苗与免疫青年人才托举项目中国肝炎防治基金会中国乙肝防控科研基金

CPMAQT_YM0334YGFK20220059

2024

中国生物制品学杂志
中华预防医学会,长春生物制品研究所有限责任公司

中国生物制品学杂志

CSTPCD
影响因子:0.417
ISSN:1004-5503
年,卷(期):2024.37(8)
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