Autologous platelet-rich plasma treatment for infected deep second-degree burn wounds:a case report
Objective To explore the feasibility of using autologous platelet-rich plasma(PRP)in the treatment of deep second-degree bums complicated with wound infection.Methods A retrospective analysis was conducted on the treatment process of a patient with deep second-degree burns and bacterial infection on the wound using autologous PRP.Clinical treatment highlights and outpatient follow-up were combined to discuss the feasibility and clinical effects of us-ing autologous PRP in the treatment of burn wounds complicated with infection.Results The patient had a deep sec-ond-degree burn with a coagulase-negative Staphylococcus infection on the left lower limb.After one week of conven-tional wound dressing and antibiotic treatment,the patient's body temperature returned to normal.However,wound heal-ing was slow and yellow secretion persisted.Subsequently,the burn wound was treated combined with topical autolo-gous PRP.The wound pain score gradually decreased from 8 to 1.After 2 weeks,the bacterial culture of the wound se-cretion was negative,and the wound healed completely after 18 days.The wound scar score decreased from 5 to 2 at 1,3 and 6 months after PRP treatment,and no obvious scar formation was observed.In the course of PRP treatment,there were no adverse reactions such as increased wound inflammation,abnormal blood routine and liver and kidney function test results.Conclusion For deep second-degree burn patients with localized wound bacterial infections who either re-fuse surgery or are not suitable for surgery,autologous PRP is a safer alternative that can effectively promote tissue re-generation and wound healing.The patient in this case achieved a curative effect in a short period of time.
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