It is necessary to improve the stability of human serum albumin in response to the complex temperature,light and other conditions during the manufacture and storage.In this paper,the stabilization effect and simple stabiliza-tion mechanism of ligands on albumin were described from the perspective of ligand binding to albumin.Through review and comparison,it can be concluded that the common ligand sodium octanoate mainly plays a role in improving thermal stability,and the common ligand N-acetyl-L-tryptophan mainly plays a role in improving antioxidant activity,N-acetyl-L-methionine has better antioxidant and anti-photooxidation than N-acetyl-L-tryptophan.
关键词
稳定性/白蛋白/辛酸钠/N-乙酰-L-色氨酸/N-乙酰-L-甲硫氨酸
Key words
albumin stability/sodium octanoate/N-acetyl-L-tryptophan/N-acetyl-L-methionine
维普
万方数据