中国输血杂志2024,Vol.37Issue(2) :209-213.DOI:10.13303/j.cjbt.issn.1004-549x.2024.02.014

同种异体富血小板血浆治疗肠造口周围皮肤损伤的探讨——附2例报道

Skin injury around enterostomy cured by allogeneic platelet-rich plasma:a report of two cases

姚红林 齐清 王淑君 沈硕 栾建凤 叶向红
中国输血杂志2024,Vol.37Issue(2) :209-213.DOI:10.13303/j.cjbt.issn.1004-549x.2024.02.014

同种异体富血小板血浆治疗肠造口周围皮肤损伤的探讨——附2例报道

Skin injury around enterostomy cured by allogeneic platelet-rich plasma:a report of two cases

姚红林 1齐清 2王淑君 2沈硕 1栾建凤 2叶向红1
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作者信息

  • 1. 东部战区总医院全军普通外科研究所,江苏南京 210002
  • 2. 东部战区总医院输血医学科,江苏南京 210002
  • 折叠

摘要

目的 探讨同种异体富血小板血浆(platelet rich plasma,PRP)应用于肠造口周围皮肤损伤治疗的可行性.方法 分析2例应用PRP治疗肠造口周围皮肤损伤患者的治疗及护理过程,并对使用的PRP进行血小板、细菌检测和5种生长因子检测.结合治疗难点与文献内容复习,探讨肠内营养支持治疗的同时予以同种异体PRP治疗肠造口周围损伤的临床治疗效果.结果 患者在清洁肠造口周围皮肤后,予以每日1次PRP治疗5d后调整为隔 日1次,分别于15 d和18 d达到治愈.结论 异体PRP是1种安全、有效的促进肠造口周围皮肤损伤的治疗方法,为临床治疗提供新的思路.

Abstract

Objective To investigate the feasibility of allogeneic platelet-rich plasma(PRP)for the treatment of skin injury around enterostomy.Methods The treatment process by PRP of 2 patients with skin injury around enterostomy was analyzed,and the PRP for each patient was tested with platelet count,bacteria and 5 growth factors.The clinical efficacy of enteral nutrition support therapy combined with allogeneic PRP was explored through analyzing treatment key points and lit-erature review.Results After cleaning the skin around enterostomy,the patients were treated with PRP once daily for 5 days,adjusted to once every other day,and cure was achieved at 15 and 18 days,respectively.Conclusion Allogeneic PRP is a safe and effective treatment to promote skin injury around enterostomy regeneration in a short time,which can pro-vide a new perspective for clinical.

关键词

富血小板血浆/肠造口/造口周围皮肤损伤

Key words

platelet-rich plasma(PRP)/enterostomy/skin injury around enterostomy

引用本文复制引用

基金项目

东部战区总医院院内课题(YYMS2021019)

东部战区总医院院内课题(22LCZLXJS52)

出版年

2024
中国输血杂志
中国输血协会 中国医学科学院输血研究所

中国输血杂志

CSTPCD
影响因子:1.279
ISSN:1004-549X
参考文献量28
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