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血浆置换在重症免疫相关性皮肤病中的应用进展

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血浆置换(plasma exchange,PE)在部分自身免疫性疾病中疗效肯定.PE主要的作用机制包括去除患者血液中的致病因子,调节患者免疫功能,补充正常的血浆成分等.在对寻常型天疱疮、中毒性表皮松解综合症和临床无肌病性皮肌炎等重症免疫相关性皮肤病的治疗中,PE的应用愈加广泛.本篇综述就近年来PE在国内外重症免疫相关性皮肤病中的应用进展做一概述,为临床重症皮肤病的治疗提供新思路.
Progress in plasma exchange for severe immune-related dermatoses
Plasma exchange(PE)is effective in a part of autoimmune diseases,and its main action mechanisms in-clude removing pathogenic factors from the patient's blood,regulating immune function,replenishing normal plasma compo-nents.The use of PE in the treatment of severe immune-related skin diseases,such as pemphigus vulgaris,toxic epidermal necrolysis and clinically amyopathic dermatomyositis,has become more widespread.This review provides an overview of the progress of PE application in severe immune-related skin diseases at home and abroad in recent years to provide new ideas for the treatment of clinical severe skin diseases.

plasma exchangesevere dermatosespemphigus vulgaristoxic epidermal necrolysisclinically amyopathic dermatomyositis

钟瑶、夏荣

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复旦大学附属华山医院输血科,上海 200040

血浆置换 重症皮肤病 寻常型天疱疮 中毒性表皮松解综合症 临床无肌病性皮肌炎

国家自然科学基金面上项目

82070197

2024

中国输血杂志
中国输血协会 中国医学科学院输血研究所

中国输血杂志

CSTPCD
影响因子:1.279
ISSN:1004-549X
年,卷(期):2024.37(2)
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