摘要
富血小板血浆(platelet rich plasma,PRP)在创面修复领域的应用越来越受到重视.然而,部分患者由于存在相对或者绝对禁忌证无法采集或者使用自体PRP,将来源于严格的捐献者筛选和标准化制备方法和技术的同种异体PRP作为自体PRP的替代品可能对此类患者具有积极意义.本文旨在就异体PRP 在创面愈合的机制、优势以及局限性、疗效和安全性进行总结和展望,为其应用于创面修复提供依据.
Abstract
The application of platelet-rich plasma(PRP)in wound repair is progressively garnering attention.However,certain patients,owing to relative or absolute contraindications,encounter impediments in the acquisition or application of autologous PRP.The utilization of homologous allogeneic PRP,sourced through rigorous donor selection and standardized preparation methodologies,as a substitute for autologous PRP,may hold favorable implications for such individuals.This ar-ticle endeavors to succinctly delineate and forecast the mechanisms,advantages,limitations,efficacy and safety of allogene-ic PRP in the context of wound healing,furnishing a foundation for its implementation in wound repair.
基金项目
四川省自然科学基金面上项目(2023NSFSC0550)
成都市医学科研项目(2023105)
国家科技期刊平台
NSTL
万方数据