中国输血杂志2024,Vol.37Issue(5) :511-515,533.DOI:10.13303/j.cjbt.issn.1004-549x.2024.05.005

抗-E、抗-c、抗-M、抗-S多重抗体分析

Multiple antibodies against-E,-c,-M,and-S:a case report

高娃 李冰 班凤禹 王秋实
中国输血杂志2024,Vol.37Issue(5) :511-515,533.DOI:10.13303/j.cjbt.issn.1004-549x.2024.05.005

抗-E、抗-c、抗-M、抗-S多重抗体分析

Multiple antibodies against-E,-c,-M,and-S:a case report

高娃 1李冰 1班凤禹 1王秋实1
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作者信息

  • 1. 中国医科大学附属盛京医院 输血科,辽宁 沈阳 110004
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摘要

目的 对 1 例存在多重抗体的肾积水伴输尿管结石合并休克老年患者进行抗体特异性鉴定.方法 微柱凝胶法进行红细胞不规则抗体筛查和抗体鉴定,酶法,抗体吸收法协助判断患者的抗体特异性;盐水试管法检测患者ABO血型鉴定、Rh血型鉴定、MNS血型.结果 患者血型:O、CCDee、NNss,患者体内检测出抗-E、抗-c、抗-M、抗-S联合抗体.结论 反复输血可能引起患者存在 1 种或者多种意外抗体,体内多种或高频率抗体的患者,可能引起鉴定困难和用血延迟.

Abstract

Objective To identify antibody specificity in an elderly patient with hydronephrosis accompanied by ureter-al stones and shock who had multiple antibodies.Methods Microcolumn gel method was used to screen unexpected anti-bodies of red blood cells and identify antibodies.Enzyme method and antibody absorption method were used to help judge the specificity of antibodies in patients.The ABO blood type,Rh blood type and MNS blood type of patient were determined by saline tube method.Results The patient′s blood types were O,CCDee,NNss,and a combination of anti-E,anti-c,anti-M and anti-S antibodies was detected.Conclusion Repeated blood transfusion may lead to the presence of one or more un-expected antibodies in patients.Patients with multiple or high-frequency antibodies may experience difficulties in identifica-tion and delayed blood use.

关键词

多重抗体/抗体鉴定

Key words

multiple antibodies/antibody identification

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基金项目

辽宁省科技厅重点研发项目(2021JH2-10300045)

出版年

2024
中国输血杂志
中国输血协会 中国医学科学院输血研究所

中国输血杂志

CSTPCD
影响因子:1.279
ISSN:1004-549X
参考文献量23
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