首页|56~60周岁固定献血浆者安全性调查分析

56~60周岁固定献血浆者安全性调查分析

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目的 探讨 55~60 岁固定献血浆者安全性,为我国单采血浆行业保留与招募 55~60 岁献浆者提供参考。方法 2018-2020 年共 9 家血液制品生产企业 55~60 岁固定献浆者及当地同龄普通人群为作为研究对象,统计固定献浆者与当地普通人群总蛋白水平、白球比[血浆白蛋白(ALB)/球蛋白(GLB),A/G]、献浆不良反应并进行回顾性分析。结果 56~60 周岁固定献血浆人群和普通人群的总蛋白质水平分别为(61。21±5。62)g/L、(60。04±6。93)g/L;白球比分别为 1。610±0。299、1。635±0。330,固定献血浆人群和普通人群的总蛋白质水平、A/G差异均具有统计学意义,固定献浆人群总蛋白水平高于普通人群,但 A/G 略低于普通人群。2018-2020 年期间,108 家浆站共采浆23 056 302人次,发生不良反应 20 932 人次,总发生率为 0。09%,无严重不良反应发生。结论 55~60 岁固定献血浆者献浆安全可靠,保留该年龄段献浆者可缓解血浆原料的供应压力。
Investigation on the safety of regular plasma donors aged 56-60 years
Objective To investigate the safety of regular plasma donors aged 55 to 60,so as to provide reference for retention and recruitment of elderly plasma donors in China.Methods Plasma donors from 9 blood products manufacturing enterprises from 2018 to 2020 and the local general population were selected as the research objects.The total protein level,albumin and globulin ratio(ALB/GLB,A/G)and adverse reactions of plasma donation of regular plasma donors and local general population were retrospectively analyzed.Results The total protein level(g/L)and A/G of plasma donors aged 56 to 60 and the general population were 61.21±5.62 vs 60.04±6.93 and 1.610±0.299 vs 1.635±0.330,respectively,and the differences were statistically significant.The total protein level of regular plasma donors was higher than that of general popu-lation,but A/G was slightly lower than that of general population.From 2018 to 2020,there were a total of 23 056 302 plas-ma donations in 108 plasma stations,and adverse reactions occurred in 20 932 donations,with a total incidence of 0.09%,with no serious adverse reactions.Conclusion It is safe for regular plasma donors aged 55 to 60 to donate plasma,and the retention of them can alleviate the pressure of plasma supply.

plasmaplasma donors aged 56 to 60adverse reaction to plasma donationage

高阳、董科成、马名立、董琰、房东红、苏雨蒙、周蓉、董德梅

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北京天坛生物制品股份有限公司,北京 100000

什邡蓉生单采血浆有限公司

国药集团兰州生物制药有限公司

国药集团上海血液制品有限公司

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血浆原料 55~60岁献浆者 献浆不良反应 年龄

2024

中国输血杂志
中国输血协会 中国医学科学院输血研究所

中国输血杂志

CSTPCD
影响因子:1.279
ISSN:1004-549X
年,卷(期):2024.37(7)
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