血液复苏是严重失血患者的关键急救措施。血液复苏液体的选用，经历了从全血到晶体液/胶体液、晶体液联合红细胞、等比例血液成分的演进过程。近 20 年来，采用低效价抗体O型全血(low titer group O whole blood，LTOWB)作为血液复苏的首选应急通用桥接复苏液，已发展成为大趋势。我们对全血在严重失血患者的应用历史和现状做一介绍，并提出我国采用LTOWB作为首选应急通用血液的进一步论证和验证研究建议。
Evolution of resuscitation fluid for hemorrhagic shock——low titer group O whole blood is becoming preferred e-mergent universal bridging resuscitation fluid
Timely and effective blood resuscitation is very important for patients with severe blood loss.The resuscitation fluids for hemorrhagic shock have evolved from whole blood to crystalloid/colloid solutions,crystalloid combined with red blood cells,to balanced blood components.In the past 20 years,it is a growing trend that low titer antibody group O whole blood(LTOWB)is used as the preferred universal bridging resuscitation fluid for emergent blood resuscitation.Herein we provide a review of the history and current status of whole blood for patients with severe bleeding and make a suggestion to launch a national implementation research program of LTOWB in China.
low titer group O whole blood(LTOWB)resuscitationhemorrhagic shock
国家科技期刊平台
NSTL
万方数据
