Therapeutic effect of intraovarian injection of autologous platelet-rich plasma for the treatment of diminished ovari-an reserve
Objective To explore the effectiveness of intraovarian injection of platelet-rich plasma(PRP)in the treat-ment of patients with diminished ovarian reserve(DOR),aiming to provide new diagnostic and therapeutic ideas for the treatment.Methods A total of 22 patients with DOR who underwent autologous PRP ovarian injection at the Reproductive Medical and Genetic Center of Qinzhou Maternal and Child Health Hospital from January 2021 to December 2023 were col-lected.Among them,12 patients underwent assisted reproductive technology for pregnancy.The patient's anti-Müllerian hor-mone(AMH),antral follicle count(AFC),basal follicle-stimulating hormone(FSH),basal luteinizing hormone(LH)and basal estradiol(E2)levels were observed.Results The levels of AMH,AFC,basal FSH,basal LH and basal E2 in 22 patients improved after treatment compared with those before treatment.Of the 12 patients who received assisted repro-duction,2 had IVF cycle canceled due to poor ovarian reaction.Ten patients obtained embryos,of which 5 obtained high-quality embryos.Conclusion Intraovarian injection of autologous PRP can effectively improve ovarian reserve function in patients with DOR.
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