Human T-lymphotropic virus infection and population characteristics of blood donors in Hainan
Objective To investigate the prevalence of human T-lymphotropic virus(HTLV) infection among voluntary blood donors and provide reference for the development of blood safety screening strategy in Hainan Province. Methods Enzyme linked immunosorbent assay (ELISA) was used to screen for HTLV,and the reactive samples were confirmed by Western blot (WB). Results A total of 326269 blood samples from 2016 to 2023 in Hainan were screened,among which 117 samples showed reactive results for initial screening,with a reactive rate of 0.036% (117/326269),and 9 were con-firmed positive by WB,with a positive rate of 0.0027%(9/326269). The prevalence of HTLV antibody varied among dif-ferent demographic groups,with a significantly higher rate among males compared to females (P<0. 05). Conclusion There are HTLV antibody positive blood donors in the voluntary blood donors in Hainan. Although it is a low prevalence area for HTLV,it is necessary to continue to expand the blood screening and conduct epidemiological investigations on positive blood donors for blood safety.