Red blood cells are the main mediators of oxygen transportation in the body. Under normal conditions,the life span of red blood cells circulating in the human body is approximately 120 days. However,after blood donation,eryth-rocytes in the storage process will eventually induce the occurrence of storage injury due to the accumulation or consumption of metabolites. This review presents a summary of recent research on the mechanism of red blood cell storage lesion,its po-tential clinical effects and corresponding strategies as follows.
red blood cell storage lesionred blood cell transfusiontransfusion-related immunomodulation