摘要
通过对肌少症相关文献检索,总结出肌少症小鼠造模方法与模型评价方案.对药物注射、衰老、肌肉萎缩和转基因 4 种造模方式的操作、优缺点、适用范围进行综述,总结肌肉功能、肌肉力量、肌肉耐力 3 种肌少症小鼠模型的评价方式,对比其优缺点,以期为肌少症的后期研究提供参考.
Abstract
We searched the literature related to sarcopenia to retrieve information on modeling method and model-evaluation schemes using sarcopenic mice.Here,we review the operation method,advantages and disadvantages,and application scopes of the four modeling method,including drug injection,aging,muscle atrophy,and transgenic mice,and summarize the method used to evaluate muscle function,muscle strength,and muscle endurance.We then compare their advantages and disadvantages,to provide a reference for subsequent research into sarcopenia.
国家科技期刊平台
NSTL
万方数据