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Micro-CT在实验动物疾病模型中的应用

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微计算机断层扫描技术(micro-computed tomography,Micro-CT)作为一种无创性技术手段,在动物实验中应用广泛,可用于辅助检测多种动物疾病模型,包括骨骼疾病、肺部疾病、口腔疾病、代谢性疾病、中耳及内耳疾病以及肿瘤等,能够提供多样性、科学性和可靠性的影像数据,因此已经成为动物实验中必不可少的实验工具之一.本综述将深入介绍Micro-CT的成像原理、梳理其在动物疾病模型研究中的应用,并总结了Micro-CT技术上的局限性并对未来的前景进行展望.
Application of Micro-CT in experimental animal disease models
Micro-computed tomography(Micro-CT)is a non-invasive technology that is widely used in animal experiments to assist in the detection of bone,lung,oral,metabolic,middle and inner ear diseases,as well as tumors,and in other animal disease models.The technique can provide diverse scientific and reliable imaging data for animal experiments and has accordingly become an indispensable experimental method in animal experiments.In this review,we introduce the imaging principles of Micro-CT,review its application in the study of animal disease models,summarize the limitations of Micro-CT technology,and consider its future prospects.

Micro-CTexperimental animalsdisease modelsapplicationtechnical defects

李淑桢、戴文敬、喻青青、田苗、张潜、李蓓

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湖北医药学院生物医药研究院,湖北 十堰 442000

湖北医药学院基础医学院,湖北 十堰 442000

Micro-CT 实验动物 疾病模型 应用 技术短板

2024

中国实验动物学报
中国实验动物学会,中国医学科学院医学实验动物研究所

中国实验动物学报

CSTPCD北大核心
影响因子:0.767
ISSN:1005-4847
年,卷(期):2024.32(5)
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