Micro-CT在实验动物疾病模型中的应用
Application of Micro-CT in experimental animal disease models
李淑桢 1戴文敬 1喻青青 1田苗 1张潜 1李蓓2
作者信息
- 1. 湖北医药学院生物医药研究院,湖北 十堰 442000
- 2. 湖北医药学院生物医药研究院,湖北 十堰 442000;湖北医药学院基础医学院,湖北 十堰 442000
- 折叠
摘要
微计算机断层扫描技术(micro-computed tomography,Micro-CT)作为一种无创性技术手段,在动物实验中应用广泛,可用于辅助检测多种动物疾病模型,包括骨骼疾病、肺部疾病、口腔疾病、代谢性疾病、中耳及内耳疾病以及肿瘤等,能够提供多样性、科学性和可靠性的影像数据,因此已经成为动物实验中必不可少的实验工具之一.本综述将深入介绍Micro-CT的成像原理、梳理其在动物疾病模型研究中的应用,并总结了Micro-CT技术上的局限性并对未来的前景进行展望.
Abstract
Micro-computed tomography(Micro-CT)is a non-invasive technology that is widely used in animal experiments to assist in the detection of bone,lung,oral,metabolic,middle and inner ear diseases,as well as tumors,and in other animal disease models.The technique can provide diverse scientific and reliable imaging data for animal experiments and has accordingly become an indispensable experimental method in animal experiments.In this review,we introduce the imaging principles of Micro-CT,review its application in the study of animal disease models,summarize the limitations of Micro-CT technology,and consider its future prospects.
关键词
Micro-CT/实验动物/疾病模型/应用/技术短板Key words
Micro-CT/experimental animals/disease models/application/technical defects引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据