中国实验动物学报2024,Vol.32Issue(11) :1456-1462.DOI:10.3969/j.issn.1005-4847.2024.11.010

水貂作为新型实验动物模型的应用研究

Application of mink as a new experimental animal model

何佳蕾 何松 张晴 张曦文 张贺 袁宝 陈健 任文陟 胡进平 丁瑜
中国实验动物学报2024,Vol.32Issue(11) :1456-1462.DOI:10.3969/j.issn.1005-4847.2024.11.010

水貂作为新型实验动物模型的应用研究

Application of mink as a new experimental animal model

何佳蕾 1何松 1张晴 1张曦文 1张贺 2袁宝 1陈健 1任文陟 1胡进平 1丁瑜1
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作者信息

  • 1. 吉林大学动物科学学院,长春 130062
  • 2. 中国农业科学院哈尔滨兽医研究所,哈尔滨 150069
  • 折叠

摘要

水貂(mink)作为一种小型珍贵的毛皮动物,不仅在经济上具有显著价值,还因其独特的生物学特征和与人类在呼吸系统、免疫反应等方面的相似性,逐渐展现出作为新型实验动物模型的巨大潜力.本文综述了水貂作为实验动物模型的应用研究,包括流感病毒动物感染、新型冠状病毒肺炎动物、动物行为、犬瘟热动物、呕吐、酶消化、睾丸退化及自伤行为模型中的应用.同时,本文强调了水貂动物福利的重要性,并提出了未来水貂作为实验动物模型在科学研究中的广阔前景,为后续水貂作为新型实验动物模型的广泛应用提供参考.

Abstract

Mink are small,fur-bearing mammals with significant economic value.They have also recently demonstrated immense potential as novel experimental animal models owing to their unique biological characteristics and similarities with humans in terms of their respiratory systems,immune responses,and other characteristics.This article comprehensively reviews applied research on the use of mink as an experimental animal model,encompassing their use as animal models for influenza virus infection,COVID-19,animal behavior,canine distemper,vomiting,enzyme digestion,testicular degeneration,and self-injurious behavior.The importance of animal welfare is also emphasized,and the broad prospects for the use of mink as an experimental animal model in scientific research are proposed,offering valuable insights and a reference for the extensive application of mink as a novel experimental animal model in the future.

关键词

水貂/实验动物模型/应用研究

Key words

mink/experimental animal model/applied research

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出版年

2024
中国实验动物学报
中国实验动物学会,中国医学科学院医学实验动物研究所

中国实验动物学报

CSTPCDCSCD北大核心
影响因子:0.767
ISSN:1005-4847
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