Biogenesis of exosomes and their role in neurodegenerative diseases
The incidence of neurodegenerative diseases(NDs)has been increasing.Current drugs targeting NDs are mainly based on relieving symptoms rather than effecting a cure,and fail to prevent disease progression.Exosomes are a subset of extracellular vesicles that can be produced by almost all cells in the human body and exert biological effects in a variety of ways after their release into the extracellular environment.Many studies have shown that the unique biological characteristics of exosomes mean that they can be used as a tool for the prevention,remission,treatment and diagnosis of NDs.This article reviews the biogenesis of exosomes and their roles in ND,to provide new ideas for the clinical treatment of these conditions.
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