Juglans mandshurica has a high medical value,because its barks,leaves and fruits can be used as medicines.In this study,chemical components of J.mandshurica and bioactivities were reviewed based on the domestic and foreign literatures in the past 20 years.So far,flavones,quinines,polyphenols,terpenoids,volatile oils and other chemical constituents have been isolated from J.mandshurica.According to pharmacological studies,both its crude extracts and specific chemical constituents show good bioactivities,including antiinflammatory,analgesic,anti-tumor,antioxidant and antiviral effects.Currently,despite some advances in its chemical constituents and pharmacological activities of J.mandshurica,there is still no intensive study on the action mechanism of its effective constituents.Therefore,further studies will be conducive to developing new medicines and making the most use of natural medical resources.