Research Survey of Extraction and Separation Technology of Effective Components in Common Chinese Medicines for Cardiovascular Disease
We searched CNKI,Wanfang data,PubMed and reference lists of identified articles(As of September l,2014),and reviewed literature,summarized extraction and separation technology of effective components in the most common Chinese medicines for cardiovascular disease.The most common extraction methods were refluxing extraction,ultrasonic extraction,microwave extraction,supercritical extraction,enzyme method,flash extraction and so on,but these researches were usually for laboratory scale.Single factor design,orthogonal design,uniform design and etc were widely used for optimization of extraction method.Water and different concentration of ethanol were always used as extraction solutions.The most common separation methods were macroporous resin,solvent extraction and precipitation method,and the later two methods usually used with macroporous adsorption resin.Some new separation techniques,such as ultrafiltration method,biological transformation technology and molecular imprinting technique,were also used.This article can provide a literature basis for extraction and separation method of Chinese medicines in cardiovascular disease.
cardiovascular diseaseChinese medicine componentSalviae Miltiorrhizae Radix et Rhizomapurification processtext mining