Effect of Integration of Habitat Processing and Pieces Processing on Main Efficiency of Sophorae Flavescentis Radix Products
Objective:To compare anti-inflammatory and antipyretic effect of Sophorae Flavescentis Radix pieces between integrated production process and traditional processing method.Method:Anti-inflammatory and detumescence effects of water extracts of two Sophorae Flavescentis Radix pieces was observed by xyleneinduced ear edema in mice.Antipyretic effect of water extracts of two kinds of Sophorae Flavescentis Radix pieces was compared in febrile rats induced by yeast.Result:Compared with the blank group,water extracts of two kinds of Sophorae Flavescentis Radix pieces could reduce the ear edema of mice,but the anti-inflammatory and detumescence effects of the integrated processed pieces was more significant,the inhibition rates of its each dose group were more than 40％.Antipyretic experiment showed that all the three doses of integrated processed pieces could decrease the body temperature of fever rats for 4 hours,and the antipyretic effect was superior to the traditional processed pieces.The contents of five main active ingredients in integrated processed pieces,such as sophocarpine,matrine,N-oxysophocarpine,sophoridine and oxymatrine,were higher than these in traditional processed pieces,their total amount was about 1.3 times to the traditional processed pieces.Conclusion:There has good similarity in the main effect of anti-inflammatory and antipyretic between integrated processed and traditional processed pieces,the integration processing method will standardize production process from the source,and it can shorten the production cycle under the premise of ensuring the quality of pieces.
NETL
NSTL
万方数据
维普
