经典名方枳实芍药散的古代文献分析和考证
Ancient Literature Analysis and Textual Research of Classic Formula Zhishi Shaoyaosan
李晨昱 1欧阳聪 1曾柔 1刘紫彦 1张烨 2林洁1
作者信息
- 1. 湖南中医药大学第一中医临床学院,长沙 410000
- 2. 深圳市福田区妇幼保健院,广东 深圳 518000
- 折叠
摘要
枳实芍药散是2023年国家中医药管理局公布的《古代经典名方目录(第二批)》中的第34首,临床运用广泛、疗效确切,但目前暂缺乏对其古代文献考证类的研究,且未有相应的中成药制剂.通过查阅、梳理相关中医古籍,对枳实芍药散的源流、药物组成、度量衡、服法、功效主治等进行分析和考证,结果显示枳实芍药散出自东汉张仲景的《金匮要略》,在历代文献中主要以"枳实芍药散"之名记载在册,该方由枳实、白芍2味药物组成,炮制方法为枳实炒炭,白芍生用,古籍中多记载该方用量为"枳实、芍药各等分,服方寸匕,日三服",折算成现代剂量为1.5 g/次(枳实0.75 g/次,白芍0.75 g/次),服用方法为将药物研磨成粉末状,用大麦粥送服,3次/d.功效为破气和血,除烦止痛,主治产后腹痛、急性盆腔炎、急性胆囊炎、肠道疾病、中风后遗症等病证,该研究通过对记载枳实芍药散的古籍文献进行梳理分析,明确该方关键信息,为推进其成药的研发提供了依据.
Abstract
Zhishi Shaoyaosan is the 34th prescription in the Catalogue of Ancient Classic Formulas(Second Batch)published by the National Administration of Traditional Chinese Medicine in 2023.It is widely used in clinical practice and has a definite curative effect.However,there is currently a lack of its ancient literature analysis and textual research,and there is no corresponding Chinese patent medicine preparation.By consulting and combing the relevant ancient books of traditional Chinese medicine,this paper analyzes and conducts textual research of the origin,composition,measurement,administration,and efficacy of Zhishi Shaoyaosan.The results show that Zhishi Shaoyaosan is derived from Essentials from the Golden Cabinet written by Zhang Zhongjing in the Eastern Han Dynasty.It is mainly recorded in the name of Zhishi Shaoyaosan in the literature of the past dynasties.The prescription is composed of Aurantii Fructus Immaturus and Paeoniae Radix Alba.The processing method is stir-frying Aurantii Fructus Immaturus to scorch and using raw Paeoniae Radix Alba.The dose of the prescription recorded in the ancient books is mainly an equal amount of Aurantii Fructus Immaturus and Paeoniae Radix Alba in one square-cun spoon,taken three times a day,which is converted into a modern dose of 1.5 g each time(0.75 g Aurantii Fructus Immaturus and 0.75 g Paeoniae Radix Alba each time).The components of the prescription are ground into powder and taken with barley porridge,three times a day.The efficacy is to break stagnated Qi,harmonize blood,and relieve restlessness and pain.It is mainly used to treat postpartum abdominal pain,acute pelvic inflammatory disease,acute cholecystitis and intestinal diseases,stroke sequelae,and other diseases.This study combs and analyzes the ancient literature recording Zhishi Shaoyaosan and clarifies the key information of the prescription,which provides a basis for promoting the research and development of its patent medicine.
关键词
经典名方/枳实芍药散/《金匮要略》/文献分析与考证/药物基原Key words
classic formula/Zhishi Shaoyaosan/Essentials from the Golden Cabinet/literature analysis and textual research/origin引用本文复制引用
出版年
2025
国家科技期刊平台
NSTL
维普
万方数据