Porcine reproductive and respiratory syndrome is a severe infectious disease caused by Porcine reproductive and respiratory syndrome virus(PRRSV).Non-structural protein 2(NSP2)encodes a multifunction protein that has a wide range of biological effects.This paper reviews NSP2 genetic variation,interactions with its own proteins and host proteins,effects on virus replication,toxicity,cell phagocytosis,regulation of host immunity and application in vaccine research and provides an important theoretical basis for further study of PRRSV pathogenic mechanism and vaccine design.
关键词
猪繁殖与呼吸综合征病毒/NSP2基因/致病机理/疫苗研究
Key words
Porcine reproductive and respiratory syndrome virus/NSP2 gene/pathogenesis/vaccine research
维普
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