Mycoplasma bovis is an important pathogen of cattle,which can cause diseases such as mastitis,arthritis and pneumonia.Mycoplasma bovis spreads all over the world and has a major adverse impact on the agricultural economy.At present,the control of M.bovis infection is seriously hindered due to the increasing trend of drug resistance and the lack of effective vaccines and treatment methods.The best way to prevent,control and even eliminate M.bovis is to use an effective vaccine.Although currently there is no M.bovis vaccine available in China,good progress has been made in related research.Based on the relevant data of M.bovine vaccine research for many years,this article reviews four aspects of infection and immune mechanism,inactivated vaccines,attenuated live vaccines and genetically engineered vaccines in order to provide ideas and references for the future development of mycoplasma vaccines.
关键词
牛支原体/感染与免疫/灭活疫苗/弱毒活疫苗/基因工程疫苗
Key words
Mycoplasma bovis/infection and immunity/inactivated vaccine/attenuated live vaccine/genetically engineered vaccine
维普
万方数据