Akabane disease is an important arthropod-borne disease of cattle and sheep caused by Akabane virus(AKAV).Akabane virus causes spontaneous abortions,premature births in pregnant females and fetus nonsuppurative encephalomyelitis,arthrogryposis-hydranencephaly syndrome in fetuses.It hass widespread reported in many countries.AKAV cause"abortion storms"that result in considerable economic losses to the livestock industry and posed a great threat to the development of livestock husbandry.Because of its wide distribution and damaging effects,Akabane virus is one of the key quarantine objects in international animal trade.In the review,we summarized progress on pathogenicity,epidemiology,clinical signs and diagnostic methods to provide a reference for prevention and control of the disease.