Progress on research and application of equine immunoglobulin
Equine immunoglobulin refers to the neutralizing antibody(mainly comprised of IgG)produced by the active immunization of horses with specific antigens.Through digestion by pepsin,the Fc fragment associated with inter-species immunogenicity is removed,and only the F(ab')2 fragment with neutralizing activity was purified.The products provide specific immunological functions and play important roles in preventing and treating many infectious diseases.This review article summarizes the structure and the function of equine immunoglobulin,as well as the research progress of equine immunoglobulin in infectious diseases such as coronavirus.It provides suggestions for making full use of the advantages of equine immunoglobulin and overcoming the bottlenecks in its research and development in the future.
国家科技期刊平台
NSTL
万方数据
维普
