首页|长角血蜱Ykt6蛋白抗东方泰勒虫感染的生物学效应

长角血蜱Ykt6蛋白抗东方泰勒虫感染的生物学效应

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  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
为了解Ykt6基因在蜱体中影响东方泰勒虫感染的生物学效果,通过长角血蜱实验室培养株和野外株,评估Ykt6蛋白对东方泰勒虫侵染长角血蜱过程中蜱的存活率、繁殖率以及对东方泰勒虫感染率等指标的生物学效果.结果显示,Ykt6基因参与了东方泰勒虫与长角血蜱之间的宿主-寄生虫相互作用.Ykt6基因的表达水平与东方泰勒虫在长角血蜱体内的存活和繁殖能力密切相关,当该基因表达水平降低时,东方泰勒虫的存活率和繁殖能力显著下降.进一步的研究发现,Ykt6基因的变异可能影响东方泰勒虫与长角血蜱之间的相互作用.一些野外长角血蜱个体具有Ykt6基因的突变,导致东方泰勒虫在长角血蜱体内的存活和繁殖能力显著下降.这一发现提示,Ykt6基因的变异可能是东方泰勒虫入侵长角血蜱的一个关键因素.总之,Ykt6基因对东方泰勒虫入侵长角血蜱具有重要影响.通过研究Ykt6基因的功能和变异,可以深入了解东方泰勒虫与长角血蜱之间的相互作用,为控制东方泰勒虫入侵提供新的思路和方法.这将有助于保护人畜健康和生态环境的平衡.
Biological effects of Ykt6 protein from Haemaphysalis longicornis for anti-infection of Theileria orientalis
In order to understand the biological effects of Ykt6 gene on the infection of Theileria orientalis in Haemaphysalis longicornis,this study evaluated the biological effects of Ykt6 protein for survival rate of ticks,and the reproduction rate,infection rate against H.longicornis during the infection process of T.orientalis between wild and cultured H.longicornis.The results showed that the Ykt6 gene was involved in the host parasite interaction between T.orientalis and H.longicornis.The expression level of the Ykt6 gene was closely related to the survival and reproductive ability of the T.orientalis in H.longicornis.When the expression level of this gene decreases,the survival rate and reproductive ability of the T.orientalis significantly decrease.Further research found that the variation of the Ykt6 gene may affect the interaction between T.orientalis and H.longicornis.Some individuals in the wild had mutations in the Ykt6 gene,leading to a significant decrease in the survival and reproductive ability of the T.orientalis in the tick.This discovery suggested that the variation of the Ykt6 gene may be a key factor in the invasion of H.longicornis by T.orientalis.In summary,the Ykt6 gene has a signi-ficant impact on the invasion of H.longicornis by the T.orientalis.By studying the function and variation of the Ykt6 gene,it is possible to gain a deeper understanding of the interaction between T.orientalis and H.longicornis,providing new ideas and methods for controlling the invasion of T.orientalis.This will help to protect human and animal health and balance the ecological environment.

Haemaphysalis longicornisTheileria orientalisYkt6 proteininfectionbiological effects

罗金、赵帅阳、车丽妍、严若锋、宋小凯、任巧云、关贵全、殷宏、刘光远、李祥瑞

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南京农业大学动物医学院教育部动物健康与食品安全国际合作联合实验室,江苏南京 210095

中国农业科学院兰州兽医研究所动物疫病防控全国重点实验室甘肃省动物寄生虫病重点实验室农业部草食动物疫病重点开放实验室,甘肃兰州 730046

长角血蜱 东方泰勒虫 Ykt6蛋白 感染 生物学效果

国家重点研发计划国家寄生虫资源库项目国家肉牛牦牛产业技术体系建设项目中国农科院科技创新工程项目中国农科院科技创新工程项目

2021YFD1800101NPRC-2019-194-30CARS-37Y2019YJ07-04Y2018PT76

2024

10.16656/j.issn.1673-4696.2024.0044

中国兽医科学
中国农业科学院兰州兽医研究所

中国兽医科学

CSTPCD北大核心
影响因子：0.524
ISSN：1673-4696
年,卷(期)：2024.54(3)
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