Advance on the interaction between sIgA and gut microbiota
Secretory immunoglobulin A(sIgA)is the most abundant antibody type in intestinal mu-cosal tissues.sIgA,together with mucus and antimicrobial peptides,forms the first line of host de-fense of intestinal epithelial cells,to protect against intestinal pathogens.sIgA can not only pre-vent the invasion of pathogenic microorganisms and neutralize toxins,but also regulate the composi-tion of intestinal microbiota,to maintain the gut homeostasis.Our review delineates the synthesis and secretion pathways of sIgA in the intestines,and systematic discussion about the interactions between gut microbiota and sIgA.
secretory immunoglobulin Agut microbiotainteractions between the gut microbiota and sIgA
国家科技期刊平台
NSTL
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