益生菌细菌素防御病毒和细菌感染的机制研究
Mechanism study of probiotics bacteriocins defense against viral and bacterial infections
李彩玉 1刘东慧 1权衡 1周继章 1陈启伟 1宫晓炜1
作者信息
- 1. 中国农业科学院兰州兽医研究所兰州大学动物医学与生物安全学院动物疫病防控全国重点实验室,甘肃兰州 730000
- 折叠
摘要
面对抗生素耐药性的巨大挑战,益生菌细菌素在提高免疫力和抗感染方面展现了显著的效果.基于此,开发以益生菌细菌素为基础的新型抗菌剂成为研究的热点.本文对益生菌细菌素的来源、分类以及它对病毒和细菌的作用机理和应用进行综述,旨在为天然产物的筛选和新型替抗产品的研发提供参考.
Abstract
Facing the enormous challenge of antibiotic resistance,probiotic bacteriocins have shown remarkable effects in improving immunity and anti-infection.Based on this,the development of new antibacterial agents about probiotics bacteriocins has become a research hotspot.This paper reviews the source,classification,mechanism of action and application of probiotic bacteriocins against viruses and bacteria,in order to provide reference for the screening of natural products and the development of novel products to replace antibiotic.
关键词
益生菌/细菌素/病毒/细菌Key words
probiotics/bacteriocins/virus/bacteria引用本文复制引用
基金项目
国家重点研发计划(2022YFC2304001)
国家自然科学基金面上项目(32172857)
畜禽免疫微生态制剂的创制及应用技术开发专项(LSY-2022-77)
出版年
2024
国家科技期刊平台
NSTL
万方数据