Research progress of animal virus-like particles vaccine expressed by Escherichia coli
The Escherichia coli expression system is widely employed for heterologous protein ex-pression due to its numerous advantages,including high expression yield,short production cycle,and low cost.It has been reported that more than 30％of recombinant protein drugs and 50％of recombinant protein preparations utilize Escherichia coli as the preferred host organism.consequently,Es-cherichia coli holds significant importance in the economical production of veterinary vaccines.This paper provides a comprehensive overview of the production and research advancements in utilizing the Escherichia coli expression system for animal virus-like particle vaccine applications.Furthermore,it summarizes the current challenges faced by this system in vaccine development along with potential solutions,aiming to offer valuable insights for future studies on animal virus-like particle vaccines employing Escherichia coli as an expression host.
国家科技期刊平台
NSTL
万方数据
