Cells are subjected to mechanical forces throughout their life cycle.This process is mediated by molecules such as LINC,Lamin A/C,TRPV4,and integrins.Recent studies have shown that mechano-transduction plays a crucial role in the development of the immune system and immune responses.After infection with pathogens,mechanotransduction regulates the activation of cellular immune responses,cytokine production,metabolism,proliferation,and transport.This review provides an in-depth analysis of the effects of mechanotransduction on the immune response,the inflammatory response,and the regula-tion of immune cell function.
国家科技期刊平台
NSTL
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