Research advances in the effect of periodontal ligament cells in regulating osteoclasts under mechanical stimula-tion
Periodontal ligament cells(PDLCs)are common cells in periodontal tissues,and they play important roles in maintaining the morphological and functional integrity,force distribution,and homeostasis protection of periodontal tis-sues.PDLCs are a kind of mechano-sensory cells that can convert mechanical force signals into biological signals,which can regulate the biological behaviors of the downstream cells.Osteoclasts(OCs)are the main functional cells during root resorption,and their viability and quantity are regulated by PDLCs.This paper reviews the research progress on how PDLCs regulate OCs under various mechanical stimulation,and aims to provide new ideas and methods for the preven-tion and treatment of root resorption.
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