非酒精性脂肪性肝病与肝移植临床研究进展
Clinical research progress of nonalcoholic fatty liver disease and liver transplantation
麦子玲 1常冰 1李异玲1
作者信息
- 1. 中国医科大学附属第一医院消化内科,辽宁沈阳 110001
- 折叠
摘要
非酒精性脂肪性肝病(NAFLD)目前已成为全球肝脏相关死亡率和发病率增长最快的疾病,目前已发现几种常见基因变异与NAFLD密切相关.文章将从NAFLD的流行病学、遗传因素以及NAFLD相关的肝移植3个方面进行重点介绍,以帮助临床医生更早地识别 NAFLD遗传易感因素,从而避免非酒精性脂肪性肝炎(NASH)及肝衰竭的发生,对于减少肝移植的治疗具有重要的临床意义.
Abstract
Nonalcoholic fatty liver disease(NAFLD)is now the fastest growing disease in the world in terms of liver-related mortality and morbidity,and several common genetic variants have been found to be strongly associated with NAFLD.The article will focus on 3 aspects of NAFLD:epidemiology,genetic elements,and NAFLD-related liver transplantation.This will help clinicians to identify genetic susceptibility factors of NAFLD earlier,so as to avoid the occurrence of NASH and liver failure,which is clinically important to reduce the treatment of liver transplantation.
关键词
非酒精性脂肪性肝病/流行病/遗传/肝移植Key words
nonalcoholic fatty liver disease/epidemiological/hereditary/liver transplantation引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据