首页|FT4水平及FT4/FT3比值鉴别垂体性甲状腺功能减退和低T3综合征的有效性研究

FT4水平及FT4/FT3比值鉴别垂体性甲状腺功能减退和低T3综合征的有效性研究

Efficiency of the FT4 level and FT4/FT3 ratio in distinguishing pituitary hypothyroidism from low T3 syndrome

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目的 探索游离甲状腺素(FT4)水平及FT4/游离三碘甲腺原氨酸(FT3)比值初步鉴别垂体性甲状腺功能减退(简称甲减)和低T3综合征的有效性.方法 收集2010年8月至2022年1月在北京朝阳医院住院的患者161例,其中垂体性甲减47例、低T3综合征65例、甲状腺功能正常者49例.对比3组患者的FT4水平及FT4/FT3比值的差异,应用ROC曲线分析FT4/FT3比值初步鉴别垂体性甲减和低T3综合征的有效性,并确定最佳临界值.结果 当FT4<0.82 ng/dL和(或)FT4/FT3比值<0.45时,诊断垂体性甲减的可能性较大.结论 FT4水平、FT4/FT3比值可以初步鉴别垂体性甲减和低T3综合征.
Objective To explore the effectiveness of FT4 level and FT4/FT3 ratio in the differential diagnosis of Pituitary hypothyroidism and low T3 syndrome.Methods From August 2010 to January 2022,clinical data of 161 cases(including 65 cases of low T3 syndrome,47 cases of pituitary hypothyroidism and 49 cases of normal thyroid function)were collected from Beijing Chaoyang Hospital.The differences in FT4 level and FTJFT3 ratio among the three groups were compared.ROC curve analysis was used to analyze the FT4 level and FT4/FT3 ratio to identify the effectiveness of pituitary hypothyroidism and low T3 syndrome,and to determine the best critical value.Results When FT4<0.82 ng/dL and/or FT4/FT3 ratio<0.45,the patient was more likely to be with pituitary hypothyroidism.Conclusion FT4 level and FT4/FT3 ratio can preliminarily distinguish pituitary hypothyroidism from low T3 syndrome.

FT4/FT3 ratiopituitary hypothyroidismlow T3 syndrome

杨彦娜、徐子博、田泽阳、杨光、苏婧如、潘清蓉、陈哲

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首都医科大学附属北京电力医院急诊科,北京 100552

首都医科大学附属北京朝阳医院教育处,北京 100020

天津医科大学,天津 300203

首都医科大学附属北京朝阳医院内分泌科,北京 100020

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FT4/FT3比值 垂体性甲状腺功能减退 低T3综合征

首都卫生发展全科医学与社区卫生科研专项首都卫生发展全科医学与社区卫生科研专项

2024-1Y-0022023-2Y-007

2024

中国实用内科杂志
中国医师协会,中国实用医学杂志社

中国实用内科杂志

CSTPCD北大核心
影响因子:1.618
ISSN:1005-2194
年,卷(期):2024.44(8)