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无创通气患者肺保护性通气的实施策略

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随着对机械通气期间肺损伤机制的不断探索,肺保护性通气策略已广泛用于有创通气患者,无创通气(NIV)患者的肺保护通气也逐渐得到关注.NIV患者肺保护通气的实施策略主要包括通过对呼吸驱动(或呼吸努力)的监测以及控制达成的呼吸力学的限制性保护、优化人机界面和参数模式的人-机同步的改善性保护、结合清醒俯卧位的肺通气均一性的保护等方面.对呼吸努力或驱动的监测与控制是NIV患者肺保护实施的核心.但目前对于N1V肺损伤的机制以及干预策略的有效性还需要进一步探索."NIV患者肺保护性通气"概念的提出既是对急性呼吸窘迫综合征新定义中非有创通气患者群体机械通气管理策略的补充,也可以推进对上述机制及策略的进一步研究.
Implementation strategies of lung protective ventilation in patients with non-invasive ventilation
With the exploration of the lung injury mechanism during mechanical ventilation,lung protective ventilation strategies have been widely used in patients receiving invasive ventilation,and the importance of lung protective ventilation during non-invasive ventilation has also been increasingly recognized.The implementation strategies of lung protective ventilation in patients with non-invasive ventilation includse protection of restricting respiratory mechanics achieved by monitoring and controlling respiratory drive/effort,protection of improving patient-ventilator synchronization by optimizing the interface and parameter or mode of the ventilator,and protection of reducing the heterogeneity by collaborating with awake prone position.The monitoring and control of respiratory effort or drive is the core of the implementation of lung protective ventilation during non-invasive ventilation.The mechanism of lung injury during non-invasive ventilation and the effectiveness of the lung protective interventions need further studies.The concept of lung protective ventilation for patients with non-invasive ventilation is not only a supplement to the management strategy in new definition of ARDS,but may also promote further studies on the mechanisms and strategies mentioned above.

non-invasive ventilationlung protective ventilationrespiratory driveacute respiratory distress syndrome

倪忠、周语嫣、罗凤鸣

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四川大学华西医院呼吸与危重症医学科,四川成都 610041

四川大学华西医院呼吸治疗科,四川成都 610041

无创通气 肺保护性通气 呼吸驱动 急性呼吸窘迫综合征

2024

中国实用内科杂志
中国医师协会,中国实用医学杂志社

中国实用内科杂志

CSTPCD北大核心
影响因子:1.618
ISSN:1005-2194
年,卷(期):2024.44(12)