摘要
Q热是由贝氏柯克斯体引起的一种普遍存在的人畜共患病,啮齿动物是重要的储存宿主.随着社会经济发展、气候环境变化和人类活动影响,人类与啮齿动物接触机会增多,Q热在人群中传播流行的风险显著增加.研究贝氏柯克斯体特征和明确重要宿主啮齿动物携带贝氏柯克斯体的情况,有助于科学评估贝氏柯克斯体通过啮齿动物传染给人的潜在风险和精准防控Q热.本研究概述了贝氏柯克斯体的病原学、致病机制、组织病理学改变、宿主动物、感染途径、感染现状等方面的现状,旨在全面认识和有效防控该疾病.
Abstract
Q fever is a widespread zoonotic disease caused by Coxiella burnetii,rodents are impor-tant reservoir hosts.With the development of society and economy,the change of climate and envi-ronment,and the influence of human activities,the chances of human contact with rodents have in-creased,and the risk of Q fever transmission epidemic in the population has significantly increased.Studying the characteristics of Coxiella burnetii and clarify the situation of important host rodents carrying Coxiella burnetii is helpful to scientifically assess the potential risk of Coxiella burnetii transmitting to humans through rodents and to prevent and control Q fever accurately.This paper provides an overview of the etiology,pathogenic mechanism,histopathological alterations,host ani-mals,routes of infection,and current status of infection of Coxiella burnetii,aiming at a compre-hensive understanding and effective prevention and control of the disease.
基金项目
国家自然科学基金(81860565)
云南省兴滇英才支持计划(YNWR-MY-2019-008)
云南省高等学校自然疫源性疾病流行病学科技创新团队项目(云教发[2020]102号)
NETL
NSTL
万方数据