猪繁殖与呼吸综合征病毒感染对宿主细胞信号转导通路影响的研究进展
Progress in study of effects of porcine reproductive and respiratory syndrome virus infection on signal transduction pathways in host cells
何松 1汤德元 1曾智勇 1王彬 1黄涛 1毛茵茗 1周飘 1陈旭 1廖正波 1袁盛林1
作者信息
- 1. 贵州大学动物科学学院,贵州贵阳 550025
- 折叠
摘要
猪繁殖与呼吸综合征病毒(porcine reproductive and respiratory syndrome virus,PRRSV)是猪繁殖与呼吸综合征(porcine reproductive and respiratory syndrome,PRRS)的病原,能够引起猪的繁殖障碍和呼吸系统疾病,目前尚未完全了解其致病机制.近年来,人们对于PRRSV感染后引起的相关信号通路变化进行了深入研究,许多信号通路传导机制不断被阐释,但仍缺乏系统性的探究,通过对PRRSV感染宿主后引起的相关信号通路变化研究做综述总结,以期为PRRSV研究提供新的思路.
Abstract
Porcine reproductive and respiratory syndrome virus(PRRSV)is the pathogen of porcine reproductive and respiratory syndrome(PRRS),which can cause reproductive disorders and respir-atory diseases in pigs,has not been fully understood.In recent years,people have conducted in-depth studies on the changes of relevant signal pathways caused by PRRSV infection,and the con-duction mechanism of many signal pathways has been constantly explained,but there is still a lack of systematic research.This paper summarizes the research advances in the relevant signal path-ways caused by PRRSV infection in host to provide new ideas for the research of PRRSV.
关键词
猪繁殖与呼吸综合征病毒/信号通路/免疫逃逸Key words
porcine reproductive and respiratory syndrome virus/signal path/immune escape引用本文复制引用
基金项目
贵州大学重点项目(黔科合平台人才20185781-8)
国家自然科学基金(31860716)
出版年
2024