摘要
新发和再发传染病严重威胁着全球卫生安全,给世界各国的经济和生活带来了巨大影响,快速检测和鉴定对传染病的监测、预警与防控至关重要.近年来,随着新型材料和科学技术日新月异的发展,检测技术不断创新与应用,逐步向着自动化、高通量、即时诊断的方向发展.本文综述了包括CRISPR系统、微流控技术、纳米PCR等传染病诊断新技术的研究进展,分析了各种新型检测技术的优势和局限性及其应用,并对检测技术的未来发展方向提出展望,旨在为人类与动物疫病的监测提供建议.
Abstract
Currently,emerging and re-emerging infectious diseases pose a serious threat to global health security,and have a huge impact on the economies and daily lives of countries around the world.Rapid detection and identification are crucial for monitoring,early warning,and prevention and control of infectious diseases.In recent years,with the rapid development of new materials and scientific technology,detection techniques have continued to innovate and be applied,progressively advancing towards automation,high throughput and real-time diagnosis.This article summarizes the research progress of new infectious disease diagnosis technologies,including CRISPR system,microfluidics technology,and nanoscale PCR,analyzes the advantages and limitations of various new detection technologies and their applications,and proposes prospects for the future develop-ment of detection technologies,in the hope of providing recommendations for monitoring human and animal diseases.