牛白血病病毒检测技术进展
Progress in detection technology of bovine leukemia virus
白和平 1郭建军 2张洪伟 2史秋梅 3王晓丹1
作者信息
- 1. 河北农业大学中兽医学院,河北保定 071000
- 2. 承德市农林科学院,河北承德 067500
- 3. 河北科技师范学院河北省预防兽医学重点实验室,河北秦皇岛 066004
- 折叠
摘要
牛白血病病毒(BLV)主要引起牛的B细胞恶性淋巴瘤,导致免疫抑制,进而使动物易感染其他疾病,除西欧外,世界各地均检出牛BLV.在人类中,存在BLV的血清抗体并在乳腺组织切片和肺肿瘤中检测到BLV的逆转录DNA,可能BLV为一种潜在的人畜共患病.目前缺乏BLV有效的治疗方法和商业化疫苗,深入了解BLV检测技术的发展,将有助于研究人员选择适合的检测方法,规避无效的检测结果,满足借助诊断防控疫病的要求.鉴于此本文对BLV细胞学检测法、核酸检测法、血清学检测法等19种检测技术进行综述,并分析比较各种方法的优缺点及适用范围,以期为BLV防控提供理论依据.
Abstract
Bovine leukemia virus(BLV)mainly causes bovine B-cell malignant lymphoma,which causes immunosuppression and leads animals susceptible to other diseases.BLV has been detected all over the world except in Western Europe.Antibodies to BLV have been detected in humans,and reverse transcribed DNA of BLV were detected in breast tissue sections and lung tumors,which in-dicate that BLV is a potential zoonotic disease.At present,there are no effective treatment methods or commercial vaccines for BLV.An in-depth understanding of the development of BLV detection technology will help researchers choose suitable detection methods,avoid invalid detection results,and meet the requirements of disease prevention and control.In view of this,this paper reviews 19 detection technologies of BLV including cytology detection,nucleic acid detection,and serology de-tection.The advantages,disadvantages,and scope of application were also analyzed,which provide theoretical guidance for the prevention and control of bovine leukemia.
关键词
牛白血病病毒/细胞学检测法/核酸检测法/血清学检测法Key words
Bovine leukemia virus/cytological detection method/nucleic acid testing method/sero-logical testing method引用本文复制引用
基金项目
中央引导地方科技发展资金项目(236Z6604G)
河北省现代农业产业技术体系建设项目肉牛产业创新团队疫病防控与减抗岗位项目(HBCT2023190201)
承德国家可持续发展议程创新示范区建设科技专项(202202F016)
出版年
2024
NETL
NSTL
万方数据