首页|纳米药物治疗鸡球虫病的研究进展

纳米药物治疗鸡球虫病的研究进展

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鸡球虫专门在鸡肠道黏膜上皮细胞内生长繁殖,危害鸡群健康.然而,传统的化学药物很难通过细胞屏障,并且易造成耐药虫株的出现以及兽药残留问题,给球虫病的防控带来巨大的挑战,因此,有必要开发新的抗球虫策略.纳米药物具有生物相容性好、易修饰且效率高等优势,提高细胞膜的穿透性的同时降低了药物的毒副作用,有望应用于球虫病防治.本文介绍了多种抗鸡球虫病的纳米药物,总结了其与传统制剂相比的优点,重点介绍纳米药物在治疗鸡球虫病中的应用,阐述目前纳米药物治疗鸡球虫病仍存在的问题,并对该领域面临的挑战和未来发展方向进行展望,以期为开发用于治疗鸡球虫病的纳米药物提供重要参考.
Research progress on nanomedicine for treating chicken coccidiosis
Chicken coccidia specialize in growing and reproducing within the epithelial cells of the chicken intestinal mucosa,posing a threat to the health of the chicken flock.However,traditional chemical drugs are difficult to pass through the cell barrier and can easily lead to the emergence of drug-resistant strains and residual veterinary drugs,posing a huge challenge to the prevention and control of coccidiosis.Therefore,it is necessary to develop new strategies against coccidiosis.Nano-drugs have the advantages of good biocompatibility,easy modification,and high efficiency,impro-ving the penetration of cell membranes while reducing drug toxicity and side effects.They are ex-pected to be applied in the prevention and treatment of coccidiosis.This article introduces various nanomedicines for treating chicken coccidiosis,summarizes their advantages compared to tradition-al formulations,focuses on the application of nanomedicines in the treatment of chicken coccidio-sis,elucidates the existing problems of nanomedicine treatment for chicken coccidiosis,and looks forward to the challenges and future development directions in this field,in order to provide impor-tant references for the development of nanomedicines for treating chicken coccidiosis.

chickencoccidiosisnanodrugsprevention and control of coccidiosis

范玉青、彭树德、白和平、史秋梅

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赵县综合职业技术教育中心,河北 赵县 051530

唐山市食品药品综合检验检测中心,河北唐山 063000

河北农业大学中兽医学院,河北保定 071000

河北科技师范学院,河北省预防兽医学重点实验室,河北秦皇岛 066004

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球虫病 纳米药物 球虫病防治

2024

中国兽医学报
吉林大学

中国兽医学报

CSTPCD北大核心
影响因子:0.702
ISSN:1005-4545
年,卷(期):2024.44(11)