急性白血病并发肺部感染诊疗的研究进展
Research Progress in Diagnosis and Treatment of Acute Leukemia Complicated with Pulmonary Infection——Review
季浩 1凌小穗 1李增政 1杨同华1
作者信息
- 1. 昆明理工大学医学院,云南昆明 650500;云南省第一人民医院血液科,云南昆明 650032
- 折叠
摘要
急性白血病是一组具有高死亡率的侵袭性恶性肿瘤,由于疾病本身和放化疗等原因导致功能性免疫细胞减少,使患者容易并发感染,其中并发肺部感染是导致患者死亡的重要原因之一.急性白血病并发肺部感染患者的早期准确诊断和合理治疗能阻止肺部感染的扩散,从而减少脓毒症、呼吸衰竭、多器官功能衰竭等严重并发症.但临床上在急性白血病并发肺部感染的诊断和治疗方面仍然存在困难,因此,本文针对急性白血病患者肺部细菌、真菌及病毒感染诊断和治疗方面的最新研究进展进行综述.
Abstract
Acute leukaemia is a group of aggressive malignancies with a high mortality rate.The reduction in functional immune cells due to the disease itself and radiotherapy/chemotherapy makes the patients susceptible to co-infections,of which pulmonary infection is a major cause of death.Early accurate diagnosis and appropriate treatment may prevent the spread of infection in patients with acute leukaemia complicated with pulmonary infection,thus reduce serious complications such as sepsis,respiratory failure and multi-organ failure.However,there are still clinical difficulties in the diagnosis and treatment of pulmonary infections in acute leukemia patients.Therefore,the current research advances in the diagnosis and treatment of bacterial,fungal and viral infections in the lungs of patients with acute leukemia were briefly summarized in this review.
关键词
急性白血病/肺部感染/诊断/治疗Key words
acute leukemia/pulmonary infection/diagnosis/treatment引用本文复制引用
基金项目
国家自然科学基金(82060810)
云南省临床医学中心开放课题(2022LCZXKF-XY-01)
出版年
2024
NETL
NSTL
万方数据