Efficacy of thoracoscopic minimally invasive surgery on primary mediastinal tumor and its influence on patients'quality of life
Objective To discuss the effect of thoracoscopic minimally invasive surgery on primary mediastinal tumor and its influence on patients'quality of life.Methods 80 patients with primary mediastinal tumor were selected and divided into a control group and a study group according to random numerical table,with 40 patients in each group.The control group was treated with conventional thoracotomy,while the study group was treated with thoracoscopic minimally invasive surgery.Record and comparison were made on clinical indicators(incision length,operative time,intraoperative blood loss,drainage time,length of hospital stay),inflammatory factors[tumor necrosis factor-ɑ(TNF-ɑ),C-reactive protein(CRP),interleukin-1β(IL-1β),interleukin-6(IL-6)],quality of life score,and complications(incision infection,mild hoarseness,coughing due to drinking water)between the two groups.Results The operative time of patients in the study group was(130.41±23.52)min,the incision length was(3.45±1.14)cm,the drainage time was(2.26±0.43)d and the length of hospital stay was(6.55±2.23)d,which were all shorter than those of(185.67±27.34)min,(14.53±2.85)cm,(4.52±0.65)d and(9.72±2.36)d in the control group;and the intraoperative blood loss of(114.56±13.21)ml was less than that of(159.71±27.35)ml in the control group.The difference was statistically significant(P<0.05).After treatment,TNF-ɑ in the study group was(50.32±5.26)pg/ml,CRP was(7.82±0.76)mg/L,IL-1β was(49.32±13.63)pg/ml,and IL-6 was(49.32±22.75)pg/ml,which were all lower than those of(78.29±5.83)pg/ml,(10.26±1.11)mg/L,(65.43±17.45)pg/ml,and(91.41±37.02)pg/ml in the control group,and the difference was statistically significant(P<0.05).After treatment,the scores of social communication ability of the study group was(80.81±8.92)points,the score of mental status was(81.46±7.92)points and the score of psychological status was(81.46±6.69)points,which were higher than those of(72.16±8.65),(73.73±7.01)and(70.67±6.85)points of the control group.The difference was statistically significant(P<0.05).After treatment,the complication rate of 5.00%in the study group was lower than that of 20.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion Thoracoscopic minimally invasive surgery for patients with primary mediastinal tumor has good clinical effect,which can reduce the occurrence of inflammation,improve the overall quality of life of patients,and reduce complications,which is worth promoting in clinical practice.
Thoracoscopic minimally invasive surgeryPrimary mediastinal tumorComplicationsQuality of life
NETL
NSTL
万方数据
维普
