Diagnostic and evaluation value of combined detection of serum SAA and CRP in coronary heart disease
Objective To analyze the diagnostic and evaluation value of serum amyloid A(SAA)and C-reactive protein(CRP)in coronary heart disease(CHD)by quantitatively detecting the levels of SAA and CRP.Methods 180 patients with coronary heart disease were selected as an experimental group and 120 healthy subjects were selected as a control group.SAA and CRP levels of the two groups were detected respectively.The levels of SAA and CRP were compared between the two groups,as well as the levels of SAA and CRP in patients with different clinical phenotypes of coronary heart disease[acute myocardial infarction(AMI),unstable angina pectoris(UAP),stable angina pectoris(SAP)].Results SAA and CRP in the experimental groups were(22.651±12.330)mg/L and(19.504±12.040)mg/L,respectively;SAA and CRP in the control group were(2.696±0.930)mg/L and(2.410±1.100)mg/L,respectively.SAA and CRP in the experimental group were significantly higher than those in the control group(P<0.05).Among patients with different clinical phenotypes,SAA and CRP in AMI patients were(40.379±5.439)and(35.699±5.065)mg/L,respectively;SAA and CRP were(15.828±1.933)and(13.094±1.764)mg/L in UAP patients,respectively;SAA and CRP were(11.746±1.931)and(9.718±1.224)mg/L in SAP patients,respectively.The levels of SAA and CRP in patients with different clinical phenotypes of the experimental group were compared,AMI>UAP>SAP(P<0.05).Conclusion There are significant differences in the levels of SAA and CRP between coronary heart disease and healthy people,and the serum levels of SAA and CRP are different in coronary heart disease patients with different clinical phenotypes.Detection of SAA and CRP levels can improve the diagnostic accuracy of coronary heart disease,and reflect the severity of coronary heart disease,so as to guide the treatment of clinicians.
Coronary heart diseaseSerum amyloid protein AC-reactive proteinDiagnosis
NETL
NSTL
万方数据
维普
