Analysis of the effect of early biochemical tests on the diagnosis of diabetic nephropathy
Objective To analyze the effect of early biochemical tests on the diagnosis of diabetic nephropathy.Methods 43 cases of diabetic nephropathy patients were selected as the observation group,and 72 healthy subjects who underwent routine physical examination during the same period were selected as the control group.Biochemical indices such as α1 microglobulin(α1-MG),blood urea nitrogen(BUN),retinol binding protein(RBP),C-reactive protein(CRP),cystatin C(CysC),homocysteine(Hcy),serum creatinine(SCr)and microalbumin(mAlb)were tested in both groups.The results of biochemical tests of the two groups were compared,and the positive rate of biochemical test in diabetic nephropathy patients was analyzed.Results The levels of CRP,CysC,α1-MG,BUN,RBP,Hcy,SCr and mAlb in the observation group were(11.53±2.05)mg/L,(2.11±0.49)mg/L,(35.16±8.02)mg/L,(13.62±2.15)mmol/L,(85.16±19.43)mg/L,(20.16±3.92)μmol/L,(175.62±15.23)μmol/L and(42.62±10.35)mg/L,which were significantly higher than those of(8.95±1.04)mg/L,(0.96±0.12)mg/L,(10.92±3.61)mg/L,(5.21±1.02)mmol/L,(50.36±10.98)mg/L,(13.26±1.28)μmol/L,(123.61±10.25)μmol/L and(21.16±8.26)mg/L in the control group,and the differences were statistically significant(P<0.05).The positive rates of CRP,CysC,α1-MG,BUN,RBP,Hcy,SCr and mAlb alone and in combination were 62.79%,72.09%,37.21%,58.14%,44.19%,69.77%,86.05%,60.47%and 97.67%.The combination of various biochemical tests in the diagnosis of diabetic nephropathy patients could obtain a higher positive detection rate.Conclusion In the clinical diagnosis of diabetic nephropathy,early biochemical tests can achieve high diagnostic efficiency.
NETL
NSTL
万方数据
维普
